Postdoc Researcher in Generative AI for Nanomedicine Design

Join TU Delft to develop generative AI methods for nanoparticle drug delivery design, at the intersection of machine learning, explainability, and pharmaceutical nanotechnology.

Job description 

We are looking for a Postdoctoral Researcher to develop generative AI methods for nanoparticle (NP) drug delivery design. You will join the research group of Dr. Sepinoud Azimi, working within the NAP4DIVE project (Horizon Europe), a consortium including AstraZeneca, TU Eindhoven, University of Gothenburg, Chalmers, and FinnAdvance.

Nanoparticle drug delivery is a high-dimensional, multi-objective design problem: formulations consist of multiple interacting components whose therapeutic behaviour changes after administration due to biological interactions (protein corona formation, degradation, payload release). Current AI approaches treat NP design as static property prediction. This project takes a fundamentally different approach: using generative models to propose novel NP formulations and coupling them with explainability methods so that design decisions can be understood, validated, and trusted.

As a postdoc, you will:

• Develop generative AI models (e.g., variational autoencoders, diffusion models, or reinforcement learning-based optimization) for NP formulation design, targeting specific therapeutic outcomes such as blood-brain barrier permeability and tumour accumulation.
• Couple generative models with counterfactual explanation methods, enabling researchers and regulators to understand why a proposed formulation is predicted to work and what minimal design changes would alter therapeutic outcomes.
• Co-supervise doctoral candidates working on related topics, including nanoparticle database curation, molecular dynamics-based transport modelling, and reinforcement learning for treatment optimization.
• Contribute to high-impact publications.
  
  

You will work alongside PhD students and interact with experimental partners across the NAP4DIVE consortium. You will have access to the DelftBlue high-performance computing cluster.

This position offers a unique opportunity to shape an emerging field. The group is building toward a long-term research programme on trustworthy AI for personalized nanomedicine, and your contributions will directly feed into this vision.

The intended start date is July–August 2026.

Click here for the full job description and application procedure.
Submission is possible until 20 April 2026